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Resistance to antibiotics: research into the benefit of humans, animals and the environment

Antibiotics for the control of these diseases and their distribution are used for serious bacterial infections. Substances inhibit or kill microorganisms. However, when used more often, bacteria can become resistant to these drugs, so they will not work. What happens when antibiotics and bacteria become environmentally friendly and drinkable for humans and animals? "At the same time, these issues also occupy human and veterinary medicine because antibiotics are used in clinics, households and animal shelters," says Dr. Med. honey. Dr. Ricarda Schmithausen of the Institute of Hygiene and Public Health (IHPH) of the University Hospital of Bonn.

"Health of humans, animals and the environment is closely related. These relations require a holistic view, "says IHPH director prof. Dr. Honey. honey. Dr. H. C. Martin Exner. This is the goal of the new "One Health – One Hygiene" working group, which is based at the University of Bonn and the University Hospital of Bonn. "Bonn is unique as a place of" one's health, "" emphasizes Schmithausen, the head of the working group.

At the University of Bonn, the Faculty of Agriculture cooperates with the Institute of Animal Science (ITW) and FoodNetCenter (FNC) and the Faculty of Medicine with the Institute of Hygiene and Public Health and the Institute for Medical Microbiology, Immunology and Parasitology (IMMIP) at the University Hospital. Bonn. The "One Health" concept also participates in the Global Health Risk Management & Hygiene Policies Master Program in cooperation with the United Nations University (UNU), the Center for Development Research (ZEF) and the German Association for International Cooperation (GIZ). ) a big role.

Potential for prevention is far from being exhausted

Scientific research develops specific recommendations for public health protection for the clinical and agricultural sector. "One health is our common ground, with which we explore all relevant issues for the distribution of antibiotics and resistant bacteria in the environment, but also in humans and animals, relationships and paths," Schmithausen says. The scientist has a doctorate on human medicine and agricultural science on this topic and he or she is not involved in complex research projects. Currently, the One Health Laboratory at the two campuses in Poppelsdorf and Venusberg in Bonn is equipped with state-of-the-art technology. The aim is to link research and use interdisciplinary skills to better protect people, animals and the environment from antibiotic-resistant bacteria. Schmithausen: "Our potential for prevention is far from exhausted."

The "One Health" working group was established as a result of the continuation of the HyReKA joint project (abbreviated HyReKA for "Biological or Hygienic-Medical Significance and Control of Antibiotic Resistant Pests in Clinical, Agricultural and Communal Wastewater and their Importance in Raw Water" the Ministry of Education and Research (BMBF). In addition, there are subsidies from partners from the economy and politics. In the HyReKA collaborative project, the researchers investigated with other scientific institutions, associations and authorities possible pathways and pathways of antibiotic-resistant bacteria, antibiotic resistance residues and residues of antibiotics in the hospital for maximum care, animal and slaughter animals, aircrafts and airports and their distribution of sewage treatment plants in water.

In addition, there are state subsidies such as the Ministry of the Environment, Agriculture, Nature and Consumer Protection in North Rhine-Westphalia (MKULNV) to study 16 bathing lakes in North Rhine-Westphalia where only very small amounts of antibiotics and appropriate resistant bacterium. Research methods developed by scientists are now also available at the State Office for Nature, Environment and Consumer Protection (LANUV) NRW for further research.

scientific contact:
Dr. honey. Dr. s. Ricarda Schmithausen
Senior Physician, Head of Department "One Health"
Institute for Hygiene and Public Health (IHPH)
Bonn University Hospital
0228 / 287-13452
E-Mail: Ricarda.Schmithausen@ukbonn.de

Prof. honey. Dr. H. C. Martin Exner
Director of the Institute for Hygiene and Public Health (IHPH)
Bonn University Hospital
0228 / 287-15520 or -15521
E-mail: Martin.Exner@ukbonn.de

idw 2019/07