Researchers find drugs for Ebola 2

Researchers find drugs for Ebola

For several years now, often fatal attacks have been striking especially in Africa throughout. The virus is spreading rapidly because the infection is already enough to touch. Now there is hope for people infected with Ebola.

Scientists have made significant progress in the fight against Ebola: a clinical trial in the Democratic Republic of the Congo has shown that two new drugs have dramatically reduced the mortality rate of Ebola patients, the NIH, which funds part of the study, said.

Treatment of Ebola patients with REGN-EB3 and mAb114 reduced the mortality rate to 29 and 34 percent respectively, the NIH reported. Untreated, the mortality rate from Ebola infected is 60 to 67 percent. Even after treatment with the usual medicines, Zmapp and remdesivir die about half of all patients.

Medications prevent the spread of the virus in the body

A final analysis of the study, which began last November, is not expected until the fall, said NIH Institute of Allergy and Infectious Disease Director Anthony Fauci. But the threshold for successful trials has already been reached with REGN-EB3, almost at mAb114. Therefore, an independent body stopped the study after 681 treatments. Initially, 725 treatments were planned. Both drugs can now be used to treat Ebola patients.

Like the Zmapp drug used so far, REGN-EB3 and mAb114 are so-called monoclonal antibodies that prevent the Ebola virus from infecting other cells in the body of the infected person.

Prevention is important in the fight against the Ebola epidemic

New scientific evidence has shown that it is possible to "drastically reduce Ebola mortality rates," Fauci said. However, fighting the Ebola epidemic is first and foremost a matter of prevention. "The best way to stop an epidemic (disease) is to have a good vaccine, as well as good contact path monitoring, isolation (from patients) and, ultimately, treatment," he said.

Wellcome Trust leader Jeremy Farrar said the study's results will "undoubtedly save lives."

Since the Ebola outbreak in the Democratic Republic of the Congo a year ago, more than 1,800 people have died in the Central African country.

The illness often ends fatal

The virus is transmitted from wild animals to humans. According to the World Health Organization (WHO), Ebola spreads to humans through direct contact with blood or other body fluids of infected humans. But sometimes even a touch is enough for an infection.

The illness often ends fatal. After infection, symptoms such as muscle pain, diarrhea and fever, internal bleeding and even organ failure occur. Prevention is therefore particularly useful and important.

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