Menopause is a risky phase of life in women because a decrease in estrogen levels increases the risk of dementia. According to studies, a particular plant substance may again reduce this risk.
Why Menopausal Women Can Benefit From Resveratrol
An American study (4) has already shown in 2001 that Resveratrol can promote women's health. A special effect is developing this phytochemical during menopause. Resveratrol should then be able to reduce the increased risk of dementia in women.
Can Resveratrol Protect Menopausal Women From Dementia?
Resveratrol is found in many plant species, but its relatively high content is found in the skin of red grapes. To be able to use Resveratrol purposefully, the substance must be used as a high-dose dietary supplement. Grape consumption is not enough here.
In a double-blind and placebo-controlled study conducted in 2016 at University of Newcastle
80 menopausal women received either 75 milligrams of resveratrol daily or placebo for 14 weeks (1).
Resveratrol has been found by researchers to significantly improve blood flow, perception and mood in the brain. They concluded that regular post-menopausal use of resveratrol can help prevent dementia. This finding was confirmed by the same research team in 2017 through two further studies (3, 5).
Why is the risk of dementia higher in women?
There are various attempts to explain why women suffer from dementia more often than men. Female hormones appear to exist, according to Alzheimer's research. Natalie Rasgon from Stanford University play a decisive role (7). Because estrogen is one of the key messengers in the central nervous system of women.
In the brain of women, estrogen until menopause acts as a protective shield for connections between nerve cells. As menopause estrogen levels decrease, the protective effect decreases and the risk of dementia increases.
Why does Resveratrol protect against dementia?
Resveratrol can support this process, according to one in 2017 at University of Bologna (2) because it is one of the phytoestrogens. Although these are not estrogens chemically, they have structural similarities with them.
For this reason, phytoestrogens such as resveratrol can bind to estrogen receptors and cause similar effects to their own estrogens in the body. These include alleviating menopausal symptoms, improving cognitive functioning in menopause, and reducing the risk of dementia.
In addition, Resveratrol has an antioxidant effect and thus protects the brain from free radicals, which, according to various studies, play a key role in the development of dementia (6).
What you need to be aware of when taking Resveratrol
It is now considered safe that artificial hormones can alleviate menopausal symptoms. But it is also suspected that the risk of serious illnesses such as stroke, heart attack and breast cancer may be increased at the same time.
In contrast, phytoestrogens like resveratrol are considered safe and can therefore be a good alternative. However, if there are estrogen-dependent diseases, the risks cannot be ruled out, so best discuss applying with a holistic doctor or alternative doctor.
When buying resveratrol supplements, you should make sure that it does not only include resveratrol, but also other herbal compounds from grapes. Often these products are labeled "resveratrol with bioflavonoids" such as. B. this Resveratrol preparation.
- Hamish Michael Evans et al., Clinical assessment of the effects of chronic resveratrol supplementation on cerebrovascular function, cognition, mood, physical function and general well-being in postmenopausal women – rational and study design, nutrients., March 2016.
- Thaung Zaw JJ et al., Do phytoestrogen supplementation improve cognition in humans? Systematic Review, Ann NY Acad Sci, September 2017
- Hamish M. Evans et al., Effects of Resveratrol on Cognitive Performance, Mood and Cerebrovascular Function in Menopausal Women; 14-week randomized placebo-controlled intervention trial, nutrient. January 2017
- Bagchi D et al., Benefits of Resveratrol in Women's Health, Medicines Exp Clin Res, 2001
- Rachel H.X. Wong et al, cerebrovascular function, cognition and general well-being of postmenopausal women improved after regular resveratrol supplements, Alzheimer's and dementia, July 2017.
- Singh A et al., Oxidative Stress: A Key Modulator in Neurodegenerative Diseases, Molecules, April 2019.
- Alexandra Bröhm Why women suffer from Alzheimer's more often than men, May 2016
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