Alzheimer is oblivious: those affected are mentally reduced, until they recognize even more relatives. But now researchers have found perhaps the first immune woman.
The 70-year-old does not have Alzheimer's: Fortunately, it is not an isolated case. But the case of a Colombian woman is something very special: her broad family has been developing Alzheimer's for generations between the ages of 40 and 50 – the most common dementia disease in the world. The large-scale extended family of about 6,000 relatives is therefore a very interesting research facility for physicians.
Resistant to Alzheimer's: Woman gives up on puzzles
For generations, a family clan from the Medellin region of Colombia have been battling a terrible disease: Alzheimer's. This form of dementia often begins insidiously, the afflicted increasingly forget thingsBut it does not stop there, mental degradation progresses throughout, more and more acquired life skills are lost, long-term and short-term memory disappears until patients with dementia in the last stage can remember anything and no longer recognize even close relatives.
Fearful scientists are exploring how dementia can be stopped. If the disease has just erupted, the course may be delayed by medication, but cure is still not possible. However, the case of the Colombian woman is currently making a shift in the field of researchThus, at the age of over 70, she was still spared a disease that had affected the whole family for decades. The woman encountered a research team led by Joseph Arbodela-Velasquez of Harvard Medical School when they screened 1,200 clan members, Focus reported.
Due to Alzheimer's protection, the body can open the door to new therapies
Scientists have found mutated PSEN1 in all family members that cause Alzheimer's disease to begin. Although the woman with immunity showed the same gene change, she did not get sick. Responsible for resistance, researchers are making another gene mutation: The so-called APOE3 variant, also a Christchurch mutation.
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Although more studies are needed to understand exactly how our own dementia protection works. But even now, the discovery of a mutation of protective genes against Alzheimer's milestone is in the study of dementia, which could be the basis for brand new Alzheimer's therapies.
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More on this topicWith these simple rules, you can enormously reduce your risk of Alzheimer's.