The study is only observational, and will not put an end to the debate surrounding the “miracle” treatment, and very controversial, promoted by the Marseille professor Didier Raoult, since it relates to hospitalized patients, suffering from severe forms of Covid-19. It is nevertheless, to date, the most serious ever conducted to evaluate, among other things, the effectiveness of hydroxychloroquine, associated or not with a macrolide (an antibiotic, Editor’s note), in the treatment of the disease.
We were unable to confirm a benefit from hydroxychloroquine or chloroquine
Four groups were given one of the four most controversial treatments. 1,868 patients received chloroquine alone, and 3,783 patients received chloroquine combined with a macrolide (either azithromycin or clarithromycin, editor’s note). The other group received either hydroxychloroquine (3,016 patients) or a cocktail of hydroxychloroquine and a macrolide (6,221 patients). The other 81,144 patients joined the control group.
And the results speak for themselves. “We were unable to confirm a benefit of hydroxychloroquine or chloroquine (…) on the prognosis of hospitalized Covid-19 patients”, write the authors. In contrast, “each of these protocols, when used for the treatment of Covid-19, was associated with a decrease in survival (…)
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